Hosted by Jane Pauley. In our cover story, David Pogue looks at what happens following the announcement of effective coronavirus vaccines. Plus: Seth Doane talks with Charlie Mackesy, the British artist behind "The Boy, the Mole, the Fox and the Horse"; Rita Braver interviews Meryl Streep, Candice Bergen and Dianne Wiest, co-stars of “Let Them All Talk”; John Blackstone meets a young portrait photographer documenting the stories of Toronto’s homeless; Tracy Smith sits down with George Clooney, star and director of “The Midnight Sky”; Faith Salie looks at those wily urban survivalists, raccoons; Mo Rocca talks with peace educator Colman McCarthy; and Kelefa Sanneh meets three scientists who spent months in isolation this COVID season in a unique locale: a New England island, home to endangered seabirds.